Vitamin B12 Deficiency

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Vitamin B12 Deficiency: Causes and Treatment

🔹 Introduction

Vitamin B12, also known as cobalamin, plays a vital role in the production of red blood cells, nerve function, and cell metabolism. A deficiency in vitamin B12 can lead to anemia, fatigue, muscle weakness, and neurological problems.



🔹 Causes of Vitamin B12 Deficiency

The body needs about 2.4 micrograms of vitamin B12 daily to function properly.
Common causes of vitamin B12 deficiency include:

  • Poor nutrition, especially diets low in animal-based foods.

  • Malabsorption disorders affecting the stomach or intestines.

  • Pancreatic diseases or Zollinger–Ellison syndrome.

  • Medications that interfere with B12 absorption, such as:

    • Metformin (used for diabetes)

    • Proton pump inhibitors (e.g., omeprazole, lansoprazole)

    • Colchicine and high doses of vitamin C


🔹 Symptoms

Vitamin B12 deficiency often develops gradually. Common signs include:

  • Persistent fatigue and dizziness

  • Irregular heartbeat

  • Pale or yellowish skin

  • Weight loss

  • Muscle weakness

  • Memory problems or confusion in advanced cases


🔹 Complications

Untreated vitamin B12 deficiency can lead to serious health issues such as:

  • Neurological disorders – tingling in the hands and feet, balance problems, or memory loss.

  • Pregnancy complications – low folate or B12 levels can increase the risk of birth defects.

  • Cognitive impairment – confusion, depression, or dementia-like symptoms.


🔹 Prevention and Treatment

A balanced diet rich in vitamin B12 can help prevent deficiency.
Recommended food sources include:

  • Beef, liver, chicken, and fish

  • Eggs and dairy products

  • Leafy greens such as spinach and broccoli, and mushrooms

If dietary intake is insufficient, vitamin B12 supplements may be prescribed as oral tablets or injections under medical supervision.


🔹 Medical Advice

To maintain healthy nerves and blood cells, it’s important to check your vitamin B12 levels regularly and consult your doctor before taking supplements.

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