Cushing’s Syndrome

What is Cushing’s Syndrome?

Cushing’s Syndrome is a hormonal disorder that occurs when the body is exposed to high levels of cortisol for a prolonged period.
It may be caused by excessive cortisol production by the body or long-term use of corticosteroid medications such as prednisone, hydrocortisone, or dexamethasone.
Risk factors include chronic asthma, rheumatoid arthritis, adrenal tumors, depression, alcohol abuse, and panic disorders.

Functions of Cortisol (“Stress Hormone”)

Reduces inflammation.
Regulates blood sugar levels.
Converts food into energy.
Maintains healthy blood pressure.

Symptoms of Cushing’s Syndrome

Weight gain in the trunk and abdomen.
Round, full face (“moon face”).
Fragile skin with purple or pink stretch marks.
Slow wound healing.
Type 2 diabetes.
Osteoporosis and bone fractures.
Skin darkening.
Growth delay in children.

In Women:

Excessive dark hair growth on the face and body.
Irregular or absent menstrual cycles.

In Men:

Reduced fertility.
Low libido.
Erectile dysfunction.

Possible Complications

Osteoporosis and fractures.
Type 2 diabetes.
Severe infections.
Heart attack and stroke.
Blood clots in the legs or lungs.

When to See a Doctor?

Consult your doctor if you experience these symptoms, especially if you have been using corticosteroid medications for a long period.

Treatment Options

Surgery: The first-line treatment to remove the underlying tumor.
Medications: To manage cortisol levels.
Radiation therapy: If surgery is not effective.

Lifestyle and Coping Tips

Engage in regular physical activity.
Ensure adequate intake of calcium and vitamin D.
Address mental health conditions.
Try massage therapy and water exercises.
Keep the brain active with cognitive exercises.

FAQs

How is Cushing’s Syndrome diagnosed?

Medical history and physical examination.
Cortisol level testing (blood, urine, or saliva).
MRI or CT scan.
Chest X-ray if needed.

What is the difference between Cushing’s Syndrome and Addison’s Disease?

Cushing’s Syndrome: Caused by excess cortisol.
Addison’s Disease: Caused by insufficient cortisol production.

Cushing’s Syndrome

Cushing’s Syndrome

What is Cushing’s Syndrome?

Functions of Cortisol (“Stress Hormone”)